Researchers Identify Genes That Predict Damage in Donated Kidneys

HI_RES_MURPHY (1)Kidney transplantation is the most common type of organ transplant surgery in the United States with over 17,000 kidney transplantations performed in 2014, according to the National Kidney Foundation. However, long-term survival still remains a challenge. While there is no actual crystal ball to predict whether a transplanted kidney will later develop fibrosis – a chronic injury that is a major cause of allograft loss after the first year – a team of researchers, led by Mount Sinai’s Barbara Murphy, MD, System Chair, Department of Medicine, Murray M. Rosenberg Professor of Medicine, Dean for Clinical Integration and Population Health, has identified a panel of 13 genes that does just that. These recently discovered 13 genes are highly predictive of decline in renal function and eventual loss of transplanted kidneys. (more…)

What is the right treatment for kidney tumors?

Guest post by Reza Mehrazin, MD, Assistant Professor of Urologic Oncology in the Department of Urology at the Icahn School of Medicine at Mount Sinai. To make an appointment with Dr. Mehrazin, call 212-241-4812.

Reza Mehrazin, MDKidney cancer, also known as renal cell carcinoma (RCC), is among the most lethal of urologic cancers. In 2015, 61,560 new cases are estimated to occur in the United States and approximately 23% of these patients are expected to die from their disease. The incidence of kidney cancer, particularly small tumors which are less than 4 cm in diameter, has been on a rise and this has largely been attributed to the increased use of cross-sectional abdominal imaging, such as CT or MRI scans. Although surgery and removal of the tumor is the standard of care for kidney cancer, there is growing understanding that in some patients who are elderly and/or have other medical conditions, the potential benefits of surgery is questionable. For these patients, active surveillance or close monitoring of the renal tumors could be a great option. There are many studies that show that an initial short-term period of observation to better understand the tumor growth rate may be safe for small kidney tumors in select candidates. (more…)

It’s Finally Here! The New US Kidney Allocation System

This article originally appeared on The American Journal of Kidney Diseases’ (AJKD) Blog

Today marks an exciting change in kidney transplantation. Although there have been adjustments to the kidney allocation system over the last 20 years, there has not been a major change. This is despite a growing waitlist and a shortage of organs. Allocation is currently driven predominantly by wait time rather than matching kidneys with appropriate recipients.

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2014 NKF NYC Kidney Walk

On Sunday, November 9, 2014 over 100 participants (consisting of Mount Sinai RMTI staff, our community partners, patients & families) proudly represented “TEAM MOUNT SINAI” as we “Talked the Talk and Walked the Walk” at the 2014 National Kidney Foundation NYC Kidney Walk.

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