The Most Common Inherited Heart Disease: Hypertrophic Cardiomyopathy

Hypertrophic Cardiomyopathy (HCM) is the most common inherited heart disease; it causes thickening of the heart muscle without a clinical cause to explain the extent of thickening observed.

HCM causes symptoms of dyspnea or shortness of breath, chest pain, exercise intolerance, syncope or fainting, and uncommonly, sudden cardiac death (SCD). It affects individuals of all ages but most commonly presents after age 30. Many patients with HCM have a relatively benign course and can have normal life expectancy, and symptoms can be managed with first-line pharmacologic agents like beta blockers or verapamil. However, a quarter of patients will experience in their course either severe disabling symptoms or SCD. (more…)

Attention Statin Patients: Are You Experiencing Muscle Aches, Weakness, Decreased Exercise Capacity, “Brain Fog”, Impaired Clarity, or Memory Loss?

If you are experiencing any of these symptoms, you may have statin intolerance.

What are statins?

Statins are a class of cholesterol lowering medication therapies that have been extensively evaluated in controlled clinical trial studies. These medications have been consistently shown to reduce the risk of a first cardiovascular event including heart attack, stroke, and death from heart disease. Also, the drugs can reduce recurrent (two or more) cardiovascular events in people with a prior heart attack, or other acute coronary syndromes that result from a reduction in blood flow to the heart muscle, or stroke. In addition, studies show statins have helped reduce the total amount of deaths worldwide overall from cardiovascular diseases. (more…)

Teaching Heart-Healthy Habits to High-Risk Children and Families

Icahn School of Medicine at Mount Sinai has received a $3.8 million grant from the American Heart Association (AHA) to promote cardiovascular health through early education and intervention programs targeting high-risk children and their parents in Harlem and the Bronx.

Mount Sinai researchers will study the genes and lifestyles of 600 preschoolers and their parents or guardians who live in these communities, which are associated with high rates of obesity, cardiovascular disease, stroke, and type 2 diabetes. The investigators will track whether the interventions lead to healthier eating habits and additional exercise. They will also examine the participants’ DNA and RNA to understand how genetics plays a role in the development of cardiovascular disease.

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“Heart Disease And Cardiovascular Disease, In General, Is A Function Of Age…and The Guidelines Say Let’s Treat Them.”

“Do you really need to treat all of these patients?”

Modern Healthcare article reported that: “ More than half of adults between ages 40 and 75 who need help managing cholesterol would be eligible for statin therapy for the prevention of heart disease on the basis of the newest American College of Cardiology and American Heart Association guidelines…The new guidelines have the potential to increase the net number of new statin prescriptions by 12.8 million.”

“With more than 115 million U.S. adults estimated to be between the ages of 40 and 75, the analysis suggests the total number of potential statin users could expand to 56 million, and the majority would be above age 60.”

(more…)

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