SinaInnovations Spotlights a New Era of Discovery

“We have learned that the impossible is possible, and advances are being made that we could not have imagined just a few years ago,” said Dennis S. Charney, MD, Anne and Joel Ehrenkranz Dean, Icahn School of Medicine at Mount Sinai, and President for Academic Affairs, Mount Sinai Health System, at the conclusion of the school’s third annual SinaInnovations conference in November.

The conference, which took place on campus Tuesday and Wednesday, November 18 and 19, respectively, focused on breakthroughs in medicine and engineering that improve human health and was sponsored jointly with Mount Sinai’s academic affiliate Rensselaer Polytechnic Institute (RPI).

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Department of Pharmacology and Systems Therapeutics Awarded More Than $31 Million in NIH Grants

Researchers at the Icahn School of Medicine at Mount Sinai have received more than $31 million from the National Institutes of Health (NIH) to create three new centers that will study how drugs interact with human cells to increase their effectiveness and decrease side effects.

A new Drug Toxicity Signature Center will be run by Ravi Iyengar, PhD, Dorothy H. and Lewis Rosenstiel Professor, Department of Pharmacology and Systems Therapeutics, who has received a grant totaling $11.6 million from the NIH. By leveraging the U.S. Food and Drug Administration’s (FDA) Adverse Event Reporting System database, the center will develop cell signatures that can be used to predict the effects of certain drugs and drug combinations.

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A Life-Saving Treatment for a Triathlete

While competing in a 1,500-meter triathlon swim in the Hudson River in August, Chris LaPak, 52, experienced sudden cardiac arrest. A Herculean rescue effort ensued, with first responders moving him quickly from a surfboard to a jet ski to a boat and finally to a pier. Attempts at cardiopulmonary resuscitation (CPR) failed, leaving Mr. LaPak—the president of a pharmaceutical printing company—without a pulse for at least nine minutes before he was finally resuscitated with an automated-external defibrillator.

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A Leading Breast Cancer Researcher and Clinician Joins Mount Sinai

Charles L. Shapiro, MD, a renowned breast cancer researcher and clinician, has been named Co-Director of the Dubin Breast Center, Director of Translational Breast Cancer Research for the Mount Sinai Health System, and Director of Survivorship Programs at The Tisch Cancer Institute at Mount Sinai.

“As a nationally recognized leader in breast medical oncology and research, Dr. Shapiro will have a pivotal role in advancing breast cancer treatment and care for our patients,” says Elisa Port, MD, Chief of Breast Surgery and Co-Director of the Dubin Breast Center at The Tisch Cancer Institute.

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Learning About Stroke

In Herald Square, on Wednesday, October 29—World Stroke Day—staff from The Mount Sinai Hospital, World Stroke Organization, and Covidien provided free blood pressure screenings, answered questions about stroke, and helped launch a global “Take 2…Tell 2” campaign. “This initiative encourages people to educate themselves and others by taking two minutes to learn about stroke risk factors, warning signs, and symptoms, and spending two minutes sharing that information,” says Stephan A. Mayer, MD, Founding Director, Institute for Critical Care Medicine, Icahn School of Medicine at Mount Sinai.

Memory Screenings at 92nd Street Y

Experts from Mount Sinai’s Alzheimer’s Disease Research Center provided free, confidential memory screenings on Tuesday, November 18, National Memory Screening Day, at the 92nd Street Y and at Linkage House, a Mount Sinai-affiliated residence for East Harlem elderly. National Memory Screening Day, spearheaded by the Alzheimer’s Foundation of America, promotes the early detection of memory problems, Alzheimer’s disease, and related illnesses, and encourages appropriate intervention.