Mount Sinai Researchers Identifies Drug with Potential to Drive Beta Cell Proliferation

Andrew Stewart, MDIn a screen of more than 100,000 potential drugs, only one, harmine, drove human insulin-producing beta cells to multiply, according to a study led by researchers at the Icahn School of Medicine at Mount Sinai, published in Nature Medicine.

Diabetes results from too few insulin-producing “beta cells” in the pancreas secreting too little insulin, the hormone required to keep blood sugar levels in the normal range. In a groundbreaking Mount Sinai study, researchers found that harmine drove the sustained division and multiplication of adult human beta cells in culture, a feat that had eluded the field for years. In addition, harmine treatment tripled the number of beta cells and led to better control of blood sugar in three groups of mice engineered to mimic human diabetes. Read more

Mount Sinai Researchers Make Diabetes Discoveries

Andrew Stewart, MD, the Irene and Dr. Arthur M. Fishberg Professor of Medicine and Director of Mount Sinai’s Diabetes, Obesity and Metabolism Institute led a team of scientists who discovered a novel mechanism that regulates the replication of insulin-producing beta cells in the pancreas. Their findings provided novel working models describing the control of cell cycle progression in the human beta cell. These discoveries offer new insights into possible therapeutic approaches to stimulate the regeneration of pancreatic beta cells in patients with Type 1 and Type 2 diabetes. Read more

A Fourteen-Year Legacy of Treatment for 9/11 Responders

Michael Crane, MD; Philip J. Landrigan, MD, MSc; and Robert O. Wright, MD, MPHIn the 14 years since the destruction of the World Trade Center (WTC), the Icahn School of Medicine at Mount Sinai has diagnosed and treated more than 20,000 first responders and survivors for 9/11-related physical and psychological issues. Area workers, residents, and responders were exposed to at least 70 carcinogens and other hazardous substances when the twin towers collapsed on September 11, 2001. Many of those involved in the recovery efforts in the days, weeks, and months after the terrorist attacks continue to require long-term medical care for conditions that have gotten worse or are just beginning to develop. Read more

Mount Sinai Launches New Kidney Center and Home Dialysis Program

Mount Sinai Launches New Kidney Center and Home Dialysis ProgramThe Mount Sinai Health System Division of Nephrology recently opened the Mount Sinai Kidney Center at East River Plaza, located at East 117th Street in East Harlem. (See photo). The 18,000-square-foot facility—which replaces The Mount Sinai Hospital’s dialysis clinic on East 94th Street—offers patients a complete range of services, including hemodialysis, peritoneal dialysis, and home hemodialysis. It features a state-of-the-art water filtration system, an increased number of stations, and easy access to public transportation. In addition, space has been allocated for an interventional suite to perform radiological procedures on-site. Read more

Free Eye Screenings for Brooklyn Seniors

Free Eye Screenings for Brooklyn SeniorsNew York Eye and Ear Infirmary of Mount Sinai’s “Eye on Senior Health” program is offering free eye examinations for Brooklyn seniors at the United Senior Citizens Center of Sunset Park. Funded by a grant from the Lavelle Fund for the Blind, Inc., the program’s goal is to widen underserved seniors’ access to health care by delivering free, physician-led ophthalmic health outreach, screenings, and treatment referrals. Eleven screenings and 30 lectures are scheduled through the end of October.

“Story Time” for Pediatric Patients

New York Eye and Ear Infirmary of Mount Sinai recently launched a “Story Time” program for pediatric patients, an initiative designed to ease their anxiety in the hospital waiting room and to acquaint them with best-selling books that also happen to have a medical-friendly theme: The Berenstain Bears Go to the Doctor, for example, and Magenta Gets Glasses from the “Blue’s Clues” series. “Story Time” occurs at two locations: the main hospital and the nearby Ear Institute.

The Susan and Leonard Feinstein Inflammatory Bowel Disease Clinical Center Opens

The Mount Sinai Hospital recently opened the Susan and Leonard Feinstein Inflammatory Bowel Disease Clinical Center at 17 East 102nd Street, a facility created to provide comprehensive care in one location for pediatric and adult patients. Inflammatory Bowel Disease (IBD) is a general classification of conditions that cause inflammation of the intestines. An estimated 1.4 million people in the United States have Crohn’s disease and ulcerative colitis. Read more

Wall Street Run and Heart Walk

More than 300 Mount Sinai Health System physicians, nurses, and staff laced up their sneakers to participate in the recent American Heart Association’s (AHA) three-mile Wall Street Run and Heart Walk. Team members raised $52,000 to help the AHA advance its cardiovascular research. They wore pink and black T-shirts designed by Jonathan P. Kyriacou, a Director of Hospital Operations, who won the “Best T-shirt” contest initiated by Lisa Allen, Administrative Director, Cardiology, Mount Sinai Beth Israel.

Marching in the 2015 Pride Parade

More than 50 Mount Sinai Health System employees and their families and friends, led by Icahn School of Medicine at Mount Sinai students Kyle Riley and Dudley Charles as parade co-captains, marched together during the 46th Annual New York City Pride Parade on Sunday, June 28. The Mount Sinai Health System walkers entered Fifth Avenue early in the parade and marched approximately three miles downtown to Washington Square and Christopher Street. A Mount Sinai St. Luke’s ambulance decorated with rainbow flags followed the group. Staff and volunteers from Mount Sinai’s Institute for Advanced Medicine also hosted booths at PrideFest, a Pride Day street festival in the West Village, distributing information about the many health services the Health System provides to the LGBT community.