Study Reveals Common Genetic Changes Are Significant in Autism

Genetic changes are responsible for roughly 60 percent of the risk for autism, and most of these variants are commonly found in the general population, according to a groundbreaking study led by Joseph D. Buxbaum, PhD, Director of the Seaver Autism Center for Research and Treatment, and Professor of Psychiatry, Neuroscience, and Genetics and Genomic Sciences at the Icahn School of Medicine at Mount Sinai.

The remaining nongenetic factors that account for roughly 40 percent of the risk for autism are not known. However, environmental factors and the interaction between genes and the environment may be a part of these nongenetic factors, says Dr. Buxbaum, the G. Harold and Leila Y. Mathers Research Professor of Geriatrics and Adult Development at Icahn School of Medicine.

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Reducing Sepsis Mortality Rates

A novel program implemented across the Emergency Department and all inpatient units at The Mount Sinai Hospital is being credited with helping the hospital achieve a three-year reduction in sepsis mortality.

The “Stop Sepsis Program” is based upon a project developed in 2011 by the Department of Emergency Medicine and the Division of Pulmonary, Critical Care and Sleep Medicine to enhance the early identification and management of patients with suspected sepsis, a condition that results from infection and can quickly become life-threatening when it impairs blood flow to organs.

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Mount Sinai to Open Kidney Stone Center

A comprehensive outpatient Kidney Stone Center, which will offer patients new minimally invasive techniques and a holistic approach to prevention, will be the first of its kind in New York City when it opens this fall in two Manhattan locations.

The Center will be headed by Mantu Gupta, MD, who was recently named Director of Endourology and Stone Disease for the Mount Sinai Health System, Chair of Urology at Mount Sinai Roosevelt and Mount Sinai St. Luke’s, and Professor of Urology.

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Eye Safety Tips Over Labor Day Weekend

In the U.S., more than 9,000 fireworks injuries happen each year, with roughly 1 in 8 fireworks injuries harming the eyes. With Labor Day weekend celebrations approaching, Dr. Ronald C. Gentile, Professor of Ophthalmology and the Chief of Ocular Trauma Service at New York Eye and Ear Infirmary of Mount Sinai, wants to remind people of some eye health and fireworks safety tips.

“Common fireworks and sparkler eye injuries include burns, lacerations, abrasions, retinal detachment, optic nerve damage and ruptured eyeball,” says Dr. Gentile. “And children are frequent victims of these injuries. As many as 30 percent of eye traumas caused by fireworks impact kids.”

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The Rundown On The Rotator Cuff

With the US Open upon us, many of us are ready to start gearing up our tennis playing. However, you might ask yourself, are my knees and shoulders up for the challenge? Many of us might be scared of the dreaded rotator cuff injury and fearful of a scenario similar to that of Novak Djokovic prior to winning Wimbledon. Luckily, Djokovic did not tear his rotator cuff and with the right knowledge about the cuff, you can avoid serious injury as well.

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Sharing My Personal Experiences With Hepatitis C Treatment (Part II)

Read Part I of my story at http://blog.mountsinai.org/blog/hepatitisc-treatment

My name is Andrew Styles and I have Hepatitis C. Hepatitis C is a liver infection caused by a virus. Hepatitis means inflammation of the liver, an organ that carries out over 500 functions that keep you healthy. I just successfully completed a new treatment for Hepatitis C (Hep C) and want to inspire others to get tested and treated. I was treated in the past with serious side effects, but this time was different.

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Teaching Heart-Healthy Habits to High-Risk Children and Families

Icahn School of Medicine at Mount Sinai has received a $3.8 million grant from the American Heart Association (AHA) to promote cardiovascular health through early education and intervention programs targeting high-risk children and their parents in Harlem and the Bronx.

Mount Sinai researchers will study the genes and lifestyles of 600 preschoolers and their parents or guardians who live in these communities, which are associated with high rates of obesity, cardiovascular disease, stroke, and type 2 diabetes. The investigators will track whether the interventions lead to healthier eating habits and additional exercise. They will also examine the participants’ DNA and RNA to understand how genetics plays a role in the development of cardiovascular disease.

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