Mount Sinai Researchers Identifies Drug with Potential to Drive Beta Cell Proliferation

Andrew Stewart, MDIn a screen of more than 100,000 potential drugs, only one, harmine, drove human insulin-producing beta cells to multiply, according to a study led by researchers at the Icahn School of Medicine at Mount Sinai, published in Nature Medicine.

Diabetes results from too few insulin-producing “beta cells” in the pancreas secreting too little insulin, the hormone required to keep blood sugar levels in the normal range. In a groundbreaking Mount Sinai study, researchers found that harmine drove the sustained division and multiplication of adult human beta cells in culture, a feat that had eluded the field for years. In addition, harmine treatment tripled the number of beta cells and led to better control of blood sugar in three groups of mice engineered to mimic human diabetes. Read more

Mount Sinai Researchers Make Diabetes Discoveries

Andrew Stewart, MD, the Irene and Dr. Arthur M. Fishberg Professor of Medicine and Director of Mount Sinai’s Diabetes, Obesity and Metabolism Institute led a team of scientists who discovered a novel mechanism that regulates the replication of insulin-producing beta cells in the pancreas. Their findings provided novel working models describing the control of cell cycle progression in the human beta cell. These discoveries offer new insights into possible therapeutic approaches to stimulate the regeneration of pancreatic beta cells in patients with Type 1 and Type 2 diabetes. Read more

A Fourteen-Year Legacy of Treatment for 9/11 Responders

Michael Crane, MD; Philip J. Landrigan, MD, MSc; and Robert O. Wright, MD, MPHIn the 14 years since the destruction of the World Trade Center (WTC), the Icahn School of Medicine at Mount Sinai has diagnosed and treated more than 20,000 first responders and survivors for 9/11-related physical and psychological issues. Area workers, residents, and responders were exposed to at least 70 carcinogens and other hazardous substances when the twin towers collapsed on September 11, 2001. Many of those involved in the recovery efforts in the days, weeks, and months after the terrorist attacks continue to require long-term medical care for conditions that have gotten worse or are just beginning to develop. Read more

Exposing Young Minds to Science and Medicine

Dennis S. Charney, MD It was a special summer of learning for the 120 area high school and college students who participated in Mount Sinai’s Center for Excellence in Youth Education’s (CEYE) research courses, clinical internships, and career preparatory programs. Established in 1975, CEYE aims to increase the presence of historically underrepresented groups in science and medicine by providing students with a wide variety of opportunities for career exploration. CEYE is housed in the Center for Multicultural and Community Affairs in the Icahn School of Medicine at Mount Sinai. Read more

Mount Sinai Launches New Kidney Center and Home Dialysis Program

Mount Sinai Launches New Kidney Center and Home Dialysis ProgramThe Mount Sinai Health System Division of Nephrology recently opened the Mount Sinai Kidney Center at East River Plaza, located at East 117th Street in East Harlem. (See photo). The 18,000-square-foot facility—which replaces The Mount Sinai Hospital’s dialysis clinic on East 94th Street—offers patients a complete range of services, including hemodialysis, peritoneal dialysis, and home hemodialysis. It features a state-of-the-art water filtration system, an increased number of stations, and easy access to public transportation. In addition, space has been allocated for an interventional suite to perform radiological procedures on-site. Read more

Free Eye Screenings for Brooklyn Seniors

Free Eye Screenings for Brooklyn SeniorsNew York Eye and Ear Infirmary of Mount Sinai’s “Eye on Senior Health” program is offering free eye examinations for Brooklyn seniors at the United Senior Citizens Center of Sunset Park. Funded by a grant from the Lavelle Fund for the Blind, Inc., the program’s goal is to widen underserved seniors’ access to health care by delivering free, physician-led ophthalmic health outreach, screenings, and treatment referrals. Eleven screenings and 30 lectures are scheduled through the end of October.

Patient Certified for New ReWalk™ System

Larry Jasinski, CEO, ReWalk Robotics, Inc.; Robert Woo; and Allan J. Kozlowski, PhDArchitect Robert Woo, who became paraplegic following a workplace injury in 2007, has become the first person in the United States to be certified to purchase the new ReWalk Personal 6.0 System to use at home. The battery-powered, robotic exoskeleton manufactured by ReWalk Robotics, Inc., enables Mr. Woo to stand up and walk with forearm crutches. The 6.0 system relocates the computer and battery from a backpack to the back pelvic area for greater comfort, and has a redesigned frame that improves knee alignment. Read more

Saluting Exemplary Patient Care At Mount Sinai Beth Israel

Mount Sinai Beth Israel President Susan Somerville, RN, personally thanked 12 hospital employees for delivering exemplary patient care at a “Dinner With the President” held Tuesday, July 21, in the 2 Dazian Boardroom, Petrie Campus. Ms. Somerville recounted that the employees had been singled out by grateful patients—through letters and emails—as especially “caring,” “professional,” “courteous,” “fantastic,” and “kind.” Ms. Somerville said of her guests: “Their warmth, love, and commitment to their patients make them people who will move our hospital into the future.” She plans to host similar dinners and breakfasts every quarter to honor outstanding employees.

Unique Liver Transplant at The Mount Sinai Hospital Restores a Patient’s Quality of Life

On a crisp, clear Sunday morning in early June, a Mount Sinai Health System team of more than 100 strong participated in the 2015 Liver Life Walk at Hudson River Park. Among the enthusiastic participants who walked the three-mile course and raised more than $20,000 to support the American Liver Foundation was Jennifer Long, a patient at Mount Sinai’s Recanati/Miller Transplantation Institute. Read more